Vessel Wall MRI in HIV-Associated Cerebral Angiitis

Multimodal MRI of Cerebral Small Vessel Disease

A remarkable pattern of subcortical vessel wall enhancement in granulomatous angiitis of the central nervous system.

Primary angiitis of the central nervous system (PACNS) is an idiopathic disorder. Clinical as well as radiological characteristics are nonspecific and heterogenic, making diagnosis delicate. We report an unusual pattern of extensive radial enhancement of the deep cerebral vasculature on magnetic resonance imaging (MRI) in a previously healthy 64-year-old woman. Our patient presented with a 6-mo...

Abeta-related angiitis: primary angiitis of the central nervous system associated with cerebral amyloid angiopathy.

Idiopathic or primary angiitis of the CNS (PACNS) and cerebral amyloid angiopathy (CAA) are unusual vasculopathies generally regarded as unrelated disorders. A few case reports have, however, described granulomatous angiitis in patients with sporadic, amyloid beta peptide (Abeta)-related CAA. Here we describe the clinical, neuroradiological and neuropathological features of nine patients with A...

Measurement of T1 in the Vessel Wall Using MRI

This thesis presents a high-resolution volumetric technique to measure the longitudinal relaxation time T1 in the vessel wall using MRI. The method of Variable Flip Angles (VFA) was applied using a new strategy for flip angle selection that allows measurement of T1 with high accuracy (< 10% mean error) and precision (T1-to-noise ratio > 10) over the wide range of anticipated values (300-3000ms)...

Intracranial vessel wall imaging at 7.0-T MRI.

BACKGROUND AND PURPOSE Conventional imaging methods cannot depict the vessel wall of intracranial arteries at sufficient resolutions. This hampers the evaluation of intracranial arterial disease. The aim of the present study was to develop a high-resolution MRI method to image intracranial vessel wall. METHODS We developed a volumetric (3-dimensional) turbo spin-echo (TSE) sequence for intrac...